Platelet rich plasma (PRP) consists of plasma sample from one’s own blood enriched with autologous platelets
Indications :
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Controversially used in Orthopaedics for possible stimulation of bone and soft tissue healing.
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Preparation technique :
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PRP is created by centrifugation of blood to separate platelet rich plasma layer from a sample of whole blood.
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Calcium chloride used to initiate platelet activation in the prepared sample of PRP.
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Platelet function
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Plays an important role in the inflammatory cascade response after injury.
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Growth factors released from platelets include :
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PDGF
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TGF-B
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VEGF
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IGF
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FGF-2
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The inflammatory cascade response initiation in itself by the platelets is the starting of healing process and the various harmones & factors released Like
PDGF
TGF-B
VEGF
IGF
FGF-2
are nothing but natural healing factors and we must utilize them for this….specially wherever nonhealing or delayed healing is imminent.